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Journal of Pediatric Oncology Nursing
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Factor V Leiden and Its Effect on Children With Cardiac Pathology

Jean A. Connor, DNSc, RN, CPNP

Department of Cardiology, Children’s Hospital, 300 Longwood Avenue, Boston, MA 02115Jean.Connor{at}cardio.chboston.org

Factor V Leiden thrombophilia, formed by a genetic mutation, slows the body’s anticoagulation response to clot formation. First described in 1994, factor V Leiden mutation has been identified as a contributing risk factor for venous thromboembolism. Although venous thromboembolism is considered rare in the pediatric population, Factor V Leiden has implications for certain at-risk pediatric patients.

Key Words: Factor V Leiden • children with congenital heart disease • genetic screening • pediatric risk factors • pediatrics • prevalence • venous thrombosis

Journal of Pediatric Oncology Nursing, Vol. 22, No. 3, 176-181 (2005)
DOI: 10.1177/1043454205275407
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