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Journal of Pediatric Oncology Nursing, Vol. 22, No. 3, 145-151 (2005)
DOI: 10.1177/1043454205275623
© 2005 Association of Pediatric Hematology/Oncology Nurses

Chronic Refractory ITP in Children: Beyond Splenectomy

Nicole Sevier, MSN, RN, CPNP

Baylor College of Medicine, Texas Children’s Cancer Center and Hematology Service, 6701 Fannin, suite 1400, MC 3-3320, Houston, TX 77030nmsevier{at}texaschildrenshospital.org

Mary Houston, MSN, RN, CPNP

Baylor College of Medicine, Texas Children’s Cancer Center and Hematology Service, Houston, TX

Idiopathic (or immune) thrombocytopenic purpura (ITP) is a relatively common hematologic condition, but one that the hematology community has failed to reach a consensus on with regard to treatment. In patients with chronic refractory ITP, there is even less agreement about treatment approaches, as this population represents a small, but challenging, fraction of the total cases of ITP. The aim of this article is to review the treatment options available for children with chronic refractory ITP, including a review of the benefits versus risks, rate of remission, and areas of ongoing and future research.

Key Words: children • ITP • treatment • chronic refractory • pediatric • idiopathic thrombocytopenia purpura • immune thrombocytopenia purpura


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